Fairly common on the island, this species can be dangerous. Consider wearing gloves if pruning to avoid any contact with or ingestion of sap or plant! Last year, I stopped to warn someone pruning a large area of these plants. The sap from blooms or sap from cutting these can be a danger.
According to the The American Journal of Psychiatry “Ingestion of Angel’s Trumpet flowers or a tea brewed from them results in an alkaloid-induced central nervous system anticholinergic syndrome characterized by symptoms such as fever, delirium, hallucinations, agitation, and persistent memory disturbances. Severe intoxication may cause flaccid paralysis, convulsions, and death.”
We have a few potentially toxic plants, including Oleander. The biggest danger with oleander is in burning the clippings after trimming.